TBLR1 (clone ), anti-human, mouse

Background:
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, th ereby allowing cofactor exchange, and transcription activation.

Alternative Name:
F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1, TBL1XR1, IRA1, TBLR1

Application Dilution: WB: 1:1000, ICC: 1:50~200, IHC: 1:50~500

Specificity: This antibody detects endogenous levels of TBLR1 and does not cross-react with related proteins

Immunogen:
Recombinant full length Human TBLR1.

MW: Predicted band size: 60KDa , Observed band size: 60Kda

Swis Prot.: Q9BZK7

Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.