TBP/TATA Binding Protein (clone 4H2), anti-human, mouse, rat

TBP/TATA Binding Protein (clone 4H2), anti-human, mouse, rat

€295.00
In stock
SKU
K000235M
Catalog Number: K000235M
Size: 100 μl
Other size: 50 μl
Isotype: Mouse IgG1
Applications: WB
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Background:
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Synonyms: GTF2D, GTF2D1, HDL4, SCA17, TFIID

Cellular Location: Nucleus

Immunogen:
Recombinant Protein

Gene Symbol: TBP/TATA Binding Protein

Gene ID: 6908

Swiss prot: P20226

Calculated MW: 35-45kDa

Recommended dilution:
WB 1:1000-2000, IHC 1:100-200

Purity:
Saturated ammonium sulfate precipitation

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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