TBX1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP9383b
Background:
TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Other Names:
T-box transcription factor TBX1, T-box protein 1, Testis-specific T-box protein, TBX1
Gene Name: TBX1 {ECO:0000303|PubMed:9268629, ECO:0000312|HGNC:HGNC:11592}
Gene ID: 6899
Primary Accession: O43435
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Other Names:
T-box transcription factor TBX1, T-box protein 1, Testis-specific T-box protein, TBX1
Gene Name: TBX1 {ECO:0000303|PubMed:9268629, ECO:0000312|HGNC:HGNC:11592}
Gene ID: 6899
Primary Accession: O43435
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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