CD41 (clone Q90), anti-human

CD41 (clone Q90), anti-human

€470.00
In stock
SKU
AC-AP63360
Catalog Number: AC-AP72747
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IF
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Background:
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Other Names:
ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41

Antigen Type: synthetic peptide

Antigen Type: ITGA2B
Gene ID: 3674
Primary Accession: P08514
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