TBX2/TBX3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61605
Background:
The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The Tbx gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. Tbx genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in Tbx genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/ brachyury, which is a transcription activator. The Tbx genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ.
Alternative Name:
T-box transcription factor TBX3, T-box protein 3, T-box transcription factor TBX2, T-box protein 2
Application Dilution: WB: 1:500~1:1000
Specificity: TBX2/TBX3 polyclonal antibody detects endogenous levels of TBX2 and TBX3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 276-320 of Human TBX2.
MW: ~ 75, 79 kDa
Swis Prot.: O15119/Q13207
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The Tbx gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. Tbx genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in Tbx genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/ brachyury, which is a transcription activator. The Tbx genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ.
Alternative Name:
T-box transcription factor TBX3, T-box protein 3, T-box transcription factor TBX2, T-box protein 2
Application Dilution: WB: 1:500~1:1000
Specificity: TBX2/TBX3 polyclonal antibody detects endogenous levels of TBX2 and TBX3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 276-320 of Human TBX2.
MW: ~ 75, 79 kDa
Swis Prot.: O15119/Q13207
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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