TBX21 antibody (clone 2F10), anti-human
€435.00
In stock
SKU
AC-AT4168a
Catalog Number: AC-AT4168a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
Request Information AC-AT4168a">Request Information
Background:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Other Names:
T-box transcription factor TBX21, T-box protein 21, T-cell-specific T-box transcription factor T-bet, Transcription factor TBLYM, TBX21, TBET, TBLYM
Antigen Type:
Recombinant Protein
Gene Name: TBX21
Gene ID: 30009
NCBI Accession: NP_037483.1
Primary Accession: Q9UL17
Other Accession: NM_013351
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Other Names:
T-box transcription factor TBX21, T-box protein 21, T-cell-specific T-box transcription factor T-bet, Transcription factor TBLYM, TBX21, TBET, TBLYM
Antigen Type:
Recombinant Protein
Gene Name: TBX21
Gene ID: 30009
NCBI Accession: NP_037483.1
Primary Accession: Q9UL17
Other Accession: NM_013351
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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