TBX5 antibody (clone 1G10), anti-human

Background:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Other Names:
T-box transcription factor TBX5, T-box protein 5, TBX5

Antigen Type:
Recombinant Protein

Gene Name: TBX5
Gene ID: 6910
NCBI Accession: NP_000183.2;NP_542448.1;NP_852259.1
Primary Accession: Q99593
Other Accession: BC027942
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .