TCEB2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16007a
Background:
This gene encodes the protein elongin B, which is asubunit of the transcription factor B (SIII) complex. The SIIIcomplex is composed of elongins A/A2, B and C. It activateselongation by RNA polymerase II by suppressing transient pausing ofthe polymerase at many sites within transcription units. Elongin Afunctions as the transcriptionally active component of the SIIIcomplex, whereas elongins B and C are regulatory subunits. ElonginA2 is specifically expressed in the testis, and capable of forminga stable complex with elongins B and C. The von Hippel-Lindau tumorsuppressor protein binds to elongins B and C, and thereby inhibitstranscription elongation. Two alternatively spliced transcriptvariants encoding different isoforms have been described for thisgene. Pseudogenes have been identified on chromosomes 11 and 13.
Other Names:
Transcription elongation factor B polypeptide 2, Elongin 18 kDa subunit, Elongin-B, EloB, RNA polymerase II transcription factor SIII subunit B, SIII p18, TCEB2
Gene Name: ELOB (HGNC:11619)
Gene ID: 6923
Primary Accession: Q15370
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes the protein elongin B, which is asubunit of the transcription factor B (SIII) complex. The SIIIcomplex is composed of elongins A/A2, B and C. It activateselongation by RNA polymerase II by suppressing transient pausing ofthe polymerase at many sites within transcription units. Elongin Afunctions as the transcriptionally active component of the SIIIcomplex, whereas elongins B and C are regulatory subunits. ElonginA2 is specifically expressed in the testis, and capable of forminga stable complex with elongins B and C. The von Hippel-Lindau tumorsuppressor protein binds to elongins B and C, and thereby inhibitstranscription elongation. Two alternatively spliced transcriptvariants encoding different isoforms have been described for thisgene. Pseudogenes have been identified on chromosomes 11 and 13.
Other Names:
Transcription elongation factor B polypeptide 2, Elongin 18 kDa subunit, Elongin-B, EloB, RNA polymerase II transcription factor SIII subunit B, SIII p18, TCEB2
Gene Name: ELOB (HGNC:11619)
Gene ID: 6923
Primary Accession: Q15370
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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