TCF2 antibody (clone 30000), anti-human
€435.00
In stock
SKU
AC-AT4185a
Catalog Number: AC-AT4185a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB
Request Information AC-AT4185a">Request Information
Background:
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription factor 2, TCF-2, Variant hepatic nuclear factor 1, vHNF1, HNF1B, TCF2
Antigen Type:
Recombinant Protein
Gene Name: HNF1B
Gene ID: 6928
NCBI Accession: NP_000449.1;NP_001159395.1
Primary Accession: P35680
Other Accession: NM_000458
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription factor 2, TCF-2, Variant hepatic nuclear factor 1, vHNF1, HNF1B, TCF2
Antigen Type:
Recombinant Protein
Gene Name: HNF1B
Gene ID: 6928
NCBI Accession: NP_000449.1;NP_001159395.1
Primary Accession: P35680
Other Accession: NM_000458
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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