TCL1B polyclonal, anti-human
€388.00
In stock
SKU
BS72241
Background:
T cell leukemia/lymphoma protein 1B (TCL-1B), also designated TML1, TCL/MTCP1-like 1, syncytiotrophoblast-specific protein and SYN-1, is involved in T cell prolymphocytic leukemia (T-PLL). TCL-1B is located within the region on human chromosome 14q32.1 which, in T cell leukemias and lymphomasis, is frequently involved in chromosomal translocations and inversions with one of the T cell receptor loci. TCL-1B is activated by chromosomal rearrangements involving the TCL1 locus. In mouse, TCL-1B is represented by five homologues, TCL-1B1-TCL-1B5. The crystal structure of TCL-1B suggests that it may play a role in the transport of small molecules such as retinoids, nucleotides and fatty acids. TCL-1B is found in both the nucleus and the cytoplasm of normal bone marrow and peripheral lymphocytes.
Alternative Name:
SYN-1, TML1
Application Dilution: WB: 1:500 - 1:1000
Specificity: TCL1B polyclonal antibody detects endogenous levels of TCL1B protein.
Immunogen:
Recombinant protein of human TCL1B
MW: 15kDa
Swis Prot.: O95988
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
T cell leukemia/lymphoma protein 1B (TCL-1B), also designated TML1, TCL/MTCP1-like 1, syncytiotrophoblast-specific protein and SYN-1, is involved in T cell prolymphocytic leukemia (T-PLL). TCL-1B is located within the region on human chromosome 14q32.1 which, in T cell leukemias and lymphomasis, is frequently involved in chromosomal translocations and inversions with one of the T cell receptor loci. TCL-1B is activated by chromosomal rearrangements involving the TCL1 locus. In mouse, TCL-1B is represented by five homologues, TCL-1B1-TCL-1B5. The crystal structure of TCL-1B suggests that it may play a role in the transport of small molecules such as retinoids, nucleotides and fatty acids. TCL-1B is found in both the nucleus and the cytoplasm of normal bone marrow and peripheral lymphocytes.
Alternative Name:
SYN-1, TML1
Application Dilution: WB: 1:500 - 1:1000
Specificity: TCL1B polyclonal antibody detects endogenous levels of TCL1B protein.
Immunogen:
Recombinant protein of human TCL1B
MW: 15kDa
Swis Prot.: O95988
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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