TCP-1θ polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5960
Background:
The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 α, β, γ, δ, ε, ζ, η and θ, each encoded by a different gene. Two ζ subunits have been described: TCP-1 ζ (also designated TCP-1 ζ1) and TCP-1 ζ2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
Alternative Name:
T-complex protein 1 subunit theta, TCP1θ, TCP-1 θ, TCP1 θ, TCP1-θ, TCP-1-theta, CCT-theta, CCTθ, CCT-θ, Renal carcinoma antigen NY-REN-15, CCT8, C21orf112, CCTQ, KIAA0002
Application Dilution: WB: 1:500~1:1000
Specificity: TCP-1θ polyclonal antibody detects endogenous levels of TCP-1θ protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 404-449 of Human TCP-1θ.
MW: ~ 59 kDa
Swis Prot.: P50990
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 α, β, γ, δ, ε, ζ, η and θ, each encoded by a different gene. Two ζ subunits have been described: TCP-1 ζ (also designated TCP-1 ζ1) and TCP-1 ζ2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
Alternative Name:
T-complex protein 1 subunit theta, TCP1θ, TCP-1 θ, TCP1 θ, TCP1-θ, TCP-1-theta, CCT-theta, CCTθ, CCT-θ, Renal carcinoma antigen NY-REN-15, CCT8, C21orf112, CCTQ, KIAA0002
Application Dilution: WB: 1:500~1:1000
Specificity: TCP-1θ polyclonal antibody detects endogenous levels of TCP-1θ protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 404-449 of Human TCP-1θ.
MW: ~ 59 kDa
Swis Prot.: P50990
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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