TDP1 (clone AT1F2), anti-human antibody
€290.00
In stock
SKU
AC-ABV11248-50
Catalog Number: AC-ABV11248-50
Size: 50 µg
Host: Mouse IgG
Applications: WB, E
Datasheet
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Size: 50 µg
Host: Mouse IgG
Applications: WB, E
Datasheet
Request Information
Background:
Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spino-cerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons.
Other Names:
Tyrosyl-DNA phosphodiesterase 1, TDP1 protein, TDP1.
Primary Accession: Q9NUW8
Gene Name: TDP1
Gene ID: 55775
Concentration (mg/ml): 1 mg/ml
Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spino-cerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons.
Other Names:
Tyrosyl-DNA phosphodiesterase 1, TDP1 protein, TDP1.
Primary Accession: Q9NUW8
Gene Name: TDP1
Gene ID: 55775
Concentration (mg/ml): 1 mg/ml
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