TEF Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP19200b
Background:
Thyrotroph embryonic factor (TEF), a transcription factor,is a member of the PAR (proline and acidic amino acid-rich)subfamily of basic region/leucine zipper (bZIP) transcriptionfactors. It is expressed in a broad range of cells and tissues inadult animals, however, during embryonic development, TEFexpression appears to be restricted to the developing anteriorpituitary gland, coincident with the appearance ofthyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to,and transactivate the TSHB promoter. It shows homology (in thefunctional domains) with other members of the PAR-bZIP subfamily oftranscription factors, which include albumin D box-binding protein(DBP), human hepatic leukemia factor (HLF) and chicken vitellogeningene-binding protein (VBP); VBP is considered the chicken homologueof TEF. Different members of the subfamily can readily formheterodimers, and share DNA-binding, and transcriptional regulatoryproperties. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Other Names:
Thyrotroph embryonic factor, TEF, KIAA1655
Gene Name: TEF
Gene ID: 7008
Primary Accession: Q10587
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Thyrotroph embryonic factor (TEF), a transcription factor,is a member of the PAR (proline and acidic amino acid-rich)subfamily of basic region/leucine zipper (bZIP) transcriptionfactors. It is expressed in a broad range of cells and tissues inadult animals, however, during embryonic development, TEFexpression appears to be restricted to the developing anteriorpituitary gland, coincident with the appearance ofthyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to,and transactivate the TSHB promoter. It shows homology (in thefunctional domains) with other members of the PAR-bZIP subfamily oftranscription factors, which include albumin D box-binding protein(DBP), human hepatic leukemia factor (HLF) and chicken vitellogeningene-binding protein (VBP); VBP is considered the chicken homologueof TEF. Different members of the subfamily can readily formheterodimers, and share DNA-binding, and transcriptional regulatoryproperties. Alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Other Names:
Thyrotroph embryonic factor, TEF, KIAA1655
Gene Name: TEF
Gene ID: 7008
Primary Accession: Q10587
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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