Terminal deoxynucleotidyl transferase, TDT (clone N153), anti-human, mouse
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In stock
SKU
BMA1039
Catalog Number: BMA1039
Size: 100 μg
Isotype: Mouse IgG2b
Reactivity: human, mouse
Application(s): WB
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Size: 100 μg
Isotype: Mouse IgG2b
Reactivity: human, mouse
Application(s): WB
Request Information
Background:
Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a DNA polymerase expressed in immature lymphocytes of the thymus and bone marrow, as well as certain leukemic cells.1TDT cDNA contains an open reading frame of 1530 base pairs (bp) corresponding to a protein containing 510 amino acids.2TDT is a useful marker in the diagnosis of acute lymphoblastic leukemia (ALL) (French-American-British [FAB] L1 and L2) and is most useful in distinguishing ALL from mature B-lymphoid neoplasms, such as Burkitt lymphoma (FAB L3) and other lymphoid malignancies.3
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of human TDT.
Recommended Application:
Western Blot, WB(1:1000)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a DNA polymerase expressed in immature lymphocytes of the thymus and bone marrow, as well as certain leukemic cells.1TDT cDNA contains an open reading frame of 1530 base pairs (bp) corresponding to a protein containing 510 amino acids.2TDT is a useful marker in the diagnosis of acute lymphoblastic leukemia (ALL) (French-American-British [FAB] L1 and L2) and is most useful in distinguishing ALL from mature B-lymphoid neoplasms, such as Burkitt lymphoma (FAB L3) and other lymphoid malignancies.3
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of human TDT.
Recommended Application:
Western Blot, WB(1:1000)
Product Form: Liquid
Purification: Peptide affinity purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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