TFAM polyclonal, anti-human, mouse

Background:
This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.

Alternative Name:
Transcription factor 6-like 1, Mitochondrial transcription factor 1, mitochondrial transcription factor A, MtTF1, mtTFA, TCF 6, TCF-6, TCF6, TCF6L1, TCF6L2, TCF6L3, TFAM, TFAM_HUMAN, Transcription factor 6, Transcription factor 6 like 2 (mitochondrial transcription factor), Transcription factor 6 like 2, Transcription factor 6-like 2, transcription factor 6-like 3, Transcription factor A, mitochondrial, Transcription factor A, mitochondrial, Transcription factor A, mitochondrial precursor,

Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200

Specificity: TFAM polyclonal antibody detects endogenous levels of TFAM protein.

Immunogen:
Recombinant full length Human TFAM.

MW: ~29 kDa

Swis Prot.: Q00059

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.