TFF1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60275
Background:
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties.
Alternative Name:
Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, PNR2, Polypeptide P1.A, hP1.A, Protein pS2, BCEI, PS2
Application Dilution: WB: 1:500~1:1000
Specificity: TFF1 polyclonal antibody detects endogenous levels of TFF1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TFF1.
MW: ~ 11 kDa
Swis Prot.: P04155
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties.
Alternative Name:
Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, PNR2, Polypeptide P1.A, hP1.A, Protein pS2, BCEI, PS2
Application Dilution: WB: 1:500~1:1000
Specificity: TFF1 polyclonal antibody detects endogenous levels of TFF1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TFF1.
MW: ~ 11 kDa
Swis Prot.: P04155
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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