Elf-4 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP69707
Catalog Number: AC-AP51555
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, E
Datasheet
Request Information
Background:
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Other Names:
ELF4; ELFR; MEF; ETS-related transcription factor Elf-4; E74-like factor 4; Myeloid Elf-1-like factor
Antigen Type: synthetic peptide
Antigen Type: ELF4 {ECO:0000312|EMBL:CAI42882.1}
Gene ID: 2000
Primary Accession: Q99607
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.
Other Names:
ELF4; ELFR; MEF; ETS-related transcription factor Elf-4; E74-like factor 4; Myeloid Elf-1-like factor
Antigen Type: synthetic peptide
Antigen Type: ELF4 {ECO:0000312|EMBL:CAI42882.1}
Gene ID: 2000
Primary Accession: Q99607
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