TGF-Beta 1 human active recombinant protein
€295.00
In stock
SKU
600335
Protein Family: Transporters, Chaperones and Folding Catalysts, Cytokines, CAM Ligands
Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction, Immune System, Cell Growth and Death, Development and Behavior, Cancers, Infectious Diseases
Alternate Names: Transforming growth factor beta-1, TGF-beta-1, TGFB1, TGFB, Latency-associated peptide, LAPDescription:
Transforming Growth Factor-beta 1 (TGF-beta1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-beta1 signals through SMAD proteins via the TGF-beta1 RI and RII receptors. Human TGF-Beta 1 is produced in HEK293. Mature human TGF-beta1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25 kDa.
Source: HEK293 cells. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is measured by the dose-dependent inhibition of IL-4-induced proliferation from mouse HT-2 cells and is typically 0.04-0.2 ng/mL. Specific activity: 2.5 x 10e7 units/mg
Accession No.: P01137
MW: 25000 Da
Sequence:
ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 5 ug of lyophilized protein. Reconstitute with 0.05 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction, Immune System, Cell Growth and Death, Development and Behavior, Cancers, Infectious Diseases
Alternate Names: Transforming growth factor beta-1, TGF-beta-1, TGFB1, TGFB, Latency-associated peptide, LAPDescription:
Transforming Growth Factor-beta 1 (TGF-beta1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-beta1 signals through SMAD proteins via the TGF-beta1 RI and RII receptors. Human TGF-Beta 1 is produced in HEK293. Mature human TGF-beta1 is a glycosylated homodimer, containing two 112 amino acids chains, with a total molecular weight of 25 kDa.
Source: HEK293 cells. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is measured by the dose-dependent inhibition of IL-4-induced proliferation from mouse HT-2 cells and is typically 0.04-0.2 ng/mL. Specific activity: 2.5 x 10e7 units/mg
Accession No.: P01137
MW: 25000 Da
Sequence:
ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 5 ug of lyophilized protein. Reconstitute with 0.05 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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