TGF-beta RII human recombinant protein
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In stock
SKU
ATGP4146
Catalog Number: ATGP4146
Size(s): 10μg, 20μg, 50μg, 100μg, 250μg, 500μg
Expression system: Baculovirus
Reactivity: human
Applications: SDS-PAGE, Bioactivity
Datasheet
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Size(s): 10μg, 20μg, 50μg, 100μg, 250μg, 500μg
Expression system: Baculovirus
Reactivity: human
Applications: SDS-PAGE, Bioactivity
Datasheet
Request Information
Background:
TGFBR2, as known as TGF-beta receptor type-2 isoform B, is a member of the serine and threonine protein kinase family and the TGF beta receptor subfamily. The type-2 receptor binds TGF-beta1 and TGF-beta3 with high affinity, and TGF-beta2 with a much lower affinity. It forms a heterodimeric complex with type1 receptor and is essential for signal transduction. Also, this protein may play an important role in TGF-beta2 binding and signaling in cells lacking TGFBR3. Recombinant human TGFBR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names:
TGF-beta receptor type-2 isoform B, TGFBR2, AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGF beta-RII, TGFR-2, TGF-beta receptor type-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II
Domain: 23-166aa
Sequence:
TIPPHVQKSV NNDMIVTDNN GAVKFPQLCK FCDVRFSTCD NQKSCMSNCS ITSICEKPQE VCVAVWRKND ENITLETVCH DPKLPYHDFI LEDAASPKCI MKEKKKPGET FFMCSCSSDE CNDNIIFSEE YNTSNPDLLL VIFQ
UniProt No.: P37173
NCBI Accession No.: NP_003233.4
Molecular Weight: 43.3 kDa (383aa)
Concentration: 0.5mg/ml (determined by absorbance at 280nm)
Formulation: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Purity: > 95% by SDS-PAGE
Bioactivity: Measured by its binding ability in a functional ELISA with Human TGF-beta3. The ED50 range ≤ 1 ug/ml.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Endotoxin: hIgG-His-Tag
Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
TGFBR2, as known as TGF-beta receptor type-2 isoform B, is a member of the serine and threonine protein kinase family and the TGF beta receptor subfamily. The type-2 receptor binds TGF-beta1 and TGF-beta3 with high affinity, and TGF-beta2 with a much lower affinity. It forms a heterodimeric complex with type1 receptor and is essential for signal transduction. Also, this protein may play an important role in TGF-beta2 binding and signaling in cells lacking TGFBR3. Recombinant human TGFBR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names:
TGF-beta receptor type-2 isoform B, TGFBR2, AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGF beta-RII, TGFR-2, TGF-beta receptor type-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II
Domain: 23-166aa
Sequence:
TIPPHVQKSV NNDMIVTDNN GAVKFPQLCK FCDVRFSTCD NQKSCMSNCS ITSICEKPQE VCVAVWRKND ENITLETVCH DPKLPYHDFI LEDAASPKCI MKEKKKPGET FFMCSCSSDE CNDNIIFSEE YNTSNPDLLL VIFQ
UniProt No.: P37173
NCBI Accession No.: NP_003233.4
Molecular Weight: 43.3 kDa (383aa)
Concentration: 0.5mg/ml (determined by absorbance at 280nm)
Formulation: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Purity: > 95% by SDS-PAGE
Bioactivity: Measured by its binding ability in a functional ELISA with Human TGF-beta3. The ED50 range ≤ 1 ug/ml.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Endotoxin: hIgG-His-Tag
Storage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
| Is Featured? | No |
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