TGF-beta (Transforming Growth Factor beta) (clone 1D11.16.8), anti-human, mouse, rat, monkey, cow, dog, hamster
€0.00
In stock
SKU
ARP-24-7040-MSM2
Catalog Number: 24-7040-MSM2
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG1, kappa
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG1, kappa
Decription:
This monoclonal antibody recognizes TGF beta 1, 2 and 3. Three TGFĪ �s have been identified in mammals. TGFĪ �1, TGFĪ �2 and TGFĪ �3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFĪ � requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFĪ �3 protein has approximately 80% identity to the mature region of both TGFĪ �1 and TGFĪ �2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFĪ �ā€™s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Ā
Synonyms: ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), Transforming growth factor beta 2 (TGF beta2 or TGFB2), Transforming growth factor beta 3 (TGF beta3 or TGFB3), Transforming Growth Factor beta (TGFbeta or TGFB)
Clone: 1D11.16.8
Isotype: Mouse IgG1, kappa
Immunogen: Bovine TGF-beta2 protein
Reactivity: human, monkey, cow, dog, mouse, rat and hamster. Others not known.
Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: Cytokine Neutralization (Order Ab without BSA/Azide)
Functional Assay (Order Ab without BSA/Azide)
Optimal dilution for a specific application should be determined.
Reactivity: Salivary gland carcinoma
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
This monoclonal antibody recognizes TGF beta 1, 2 and 3. Three TGFĪ �s have been identified in mammals. TGFĪ �1, TGFĪ �2 and TGFĪ �3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFĪ � requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFĪ �3 protein has approximately 80% identity to the mature region of both TGFĪ �1 and TGFĪ �2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFĪ �ā€™s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Ā
Synonyms: ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), Transforming growth factor beta 2 (TGF beta2 or TGFB2), Transforming growth factor beta 3 (TGF beta3 or TGFB3), Transforming Growth Factor beta (TGFbeta or TGFB)
Clone: 1D11.16.8
Isotype: Mouse IgG1, kappa
Immunogen: Bovine TGF-beta2 protein
Reactivity: human, monkey, cow, dog, mouse, rat and hamster. Others not known.
Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applications: Cytokine Neutralization (Order Ab without BSA/Azide)
Functional Assay (Order Ab without BSA/Azide)
Optimal dilution for a specific application should be determined.
Reactivity: Salivary gland carcinoma
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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