TGFβ RII polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7266
Background:
TGFβs mediate their activity by high affinity binding to the type II receptor (TGFβ RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses the type II receptor requires both its kinase activity and association with a TGFβ-binding protein, designated the type I receptor. Two independent groups have recently described the cloning and sequence analysis of genes encoding TGFβ type I receptor proteins designated ALK-5 (TβR-1) and TSR-1, respectively.
Alternative Name:
TGF-beta receptor type-2, TGFR-2, TGFR2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, TGFBR2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
Specificity: TGFβ RII polyclonal antibody detects endogenous levels of TGFβ RII protein.
Immunogen:
Recombinant full length Human TGFβ RII.
MW: ~ 65 kDa
Swis Prot.: P37173
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
TGFβs mediate their activity by high affinity binding to the type II receptor (TGFβ RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses the type II receptor requires both its kinase activity and association with a TGFβ-binding protein, designated the type I receptor. Two independent groups have recently described the cloning and sequence analysis of genes encoding TGFβ type I receptor proteins designated ALK-5 (TβR-1) and TSR-1, respectively.
Alternative Name:
TGF-beta receptor type-2, TGFR-2, TGFR2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, TGFBR2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
Specificity: TGFβ RII polyclonal antibody detects endogenous levels of TGFβ RII protein.
Immunogen:
Recombinant full length Human TGFβ RII.
MW: ~ 65 kDa
Swis Prot.: P37173
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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