TGFB1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12348a
Background:
TGFB1 is a member of the transforming growthfactor beta (TGFB) family of cytokines, which are multifunctionalpeptides that regulate proliferation, differentiation, adhesion,migration, and other functions in many cell types. Many cells haveTGFB receptors, and the protein positively and negatively regulatesmany other growth factors. The secreted protein is cleaved into alatency-associated peptide (LAP) and a mature TGFB1 peptide, and isfound in either a latent form composed of a TGFB1 homodimer, a LAPhomodimer, and a latent TGFB1-binding protein, or in an active formcomposed of a TGFB1 homodimer. The mature peptide may also formheterodimers with other TGFB family members. This gene isfrequently upregulated in tumor cells, and mutations in this generesult in Camurati-Engelmann disease.
Other Names:
Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB
Gene Name: TGFB1 (HGNC:11766)
Gene ID: 7040
Primary Accession: P01137
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
TGFB1 is a member of the transforming growthfactor beta (TGFB) family of cytokines, which are multifunctionalpeptides that regulate proliferation, differentiation, adhesion,migration, and other functions in many cell types. Many cells haveTGFB receptors, and the protein positively and negatively regulatesmany other growth factors. The secreted protein is cleaved into alatency-associated peptide (LAP) and a mature TGFB1 peptide, and isfound in either a latent form composed of a TGFB1 homodimer, a LAPhomodimer, and a latent TGFB1-binding protein, or in an active formcomposed of a TGFB1 homodimer. The mature peptide may also formheterodimers with other TGFB family members. This gene isfrequently upregulated in tumor cells, and mutations in this generesult in Camurati-Engelmann disease.
Other Names:
Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB
Gene Name: TGFB1 (HGNC:11766)
Gene ID: 7040
Primary Accession: P01137
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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