TGIF2LY polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60528
Background:
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species. It also functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and control of gene expression. TGIF2LY (TGFB-induced factor homeobox 2-like, Y-linked), also known as TGIFLY, is a 185 amino acid testis-specific nuclear protein that functions as a transcriptional regulator during spermatid maturation. TGIF2LY belongs to the TALE/TGIF homeobox family and contains one homeobox DNA-binding domain. The gene encoding TGIF2LY maps within a male specific region of chromosome Y, in a region implied to form following a large X-to-Y transposition. The C-terminal region of TGIF2LY differs from the C-terminal region of its chromosome X homolog TGIF2LX, which suggests that TGIF2LY may act as a competitor or regulator of TGIF2LX.
Alternative Name:
Homeobox protein TGIF2LX, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X, TGIF2LX, TGIFLX
Application Dilution: WB: 1:500~1:1000
Specificity: TGIF2LY polyclonal antibody detects endogenous levels of TGIF2LY protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TGIF2LY
MW: ~ 21 kDa
Swis Prot.: Q8IUE1/Q8IUE0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species. It also functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and control of gene expression. TGIF2LY (TGFB-induced factor homeobox 2-like, Y-linked), also known as TGIFLY, is a 185 amino acid testis-specific nuclear protein that functions as a transcriptional regulator during spermatid maturation. TGIF2LY belongs to the TALE/TGIF homeobox family and contains one homeobox DNA-binding domain. The gene encoding TGIF2LY maps within a male specific region of chromosome Y, in a region implied to form following a large X-to-Y transposition. The C-terminal region of TGIF2LY differs from the C-terminal region of its chromosome X homolog TGIF2LX, which suggests that TGIF2LY may act as a competitor or regulator of TGIF2LX.
Alternative Name:
Homeobox protein TGIF2LX, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X, TGIF2LX, TGIFLX
Application Dilution: WB: 1:500~1:1000
Specificity: TGIF2LY polyclonal antibody detects endogenous levels of TGIF2LY protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TGIF2LY
MW: ~ 21 kDa
Swis Prot.: Q8IUE1/Q8IUE0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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