THADA polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8729
Background:
THADA (thyroid adenoma associated), also known as GITA, is a 1,953 amino acid protein that is expressed in testis, thyroid, pancreas, stomach and small intestine. Chromosomal aberrations in the gene encoding THADA are associated with benign thyroid adenomas, suggesting a potential role for THADA in tumorigenesis. The THADA gene maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.
Alternative Name:
Thyroid adenoma-associated protein, Gene inducing thyroid adenomas protein, THADA, GITA, KIAA1767
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: THADA polyclonal antibody detects endogenous levels of THADA protein.
Immunogen:
Recombinant full length Human THADA.
MW: ~ 220kDa
Swis Prot.: Q6YHU6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
THADA (thyroid adenoma associated), also known as GITA, is a 1,953 amino acid protein that is expressed in testis, thyroid, pancreas, stomach and small intestine. Chromosomal aberrations in the gene encoding THADA are associated with benign thyroid adenomas, suggesting a potential role for THADA in tumorigenesis. The THADA gene maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.
Alternative Name:
Thyroid adenoma-associated protein, Gene inducing thyroid adenomas protein, THADA, GITA, KIAA1767
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: THADA polyclonal antibody detects endogenous levels of THADA protein.
Immunogen:
Recombinant full length Human THADA.
MW: ~ 220kDa
Swis Prot.: Q6YHU6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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