CD141 (Thrombomodulin) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5650
Background:
Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
Alternative Name:
Thrombomodulin, TM, Fetomodulin, CD141, THBD, THRM
Application Dilution: WB: 1:500~1:1000
Specificity: Thrombomodulin polyclonal antibody detects endogenous levels of Thrombomodulin protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 530-575 of Human Thrombomodulin.
MW: ~ 60, 105 kDa
Swis Prot.: P07204
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
Alternative Name:
Thrombomodulin, TM, Fetomodulin, CD141, THBD, THRM
Application Dilution: WB: 1:500~1:1000
Specificity: Thrombomodulin polyclonal antibody detects endogenous levels of Thrombomodulin protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 530-575 of Human Thrombomodulin.
MW: ~ 60, 105 kDa
Swis Prot.: P07204
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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