MALT1 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP70813
Background:
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. Involved in the induction of T helper 17 cells (Th17) differentiation. Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation (By similarity).
Other Names:
MALT1; MLT; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT lymphoma-associated translocation; Paracaspase
Antigen Type: synthetic peptide
Antigen Type: MALT1 {ECO:0000303|PubMed:10523859, ECO:0000312|HGNC:HGNC:6819}
Gene ID: 10892
Primary Accession: Q9UDY8
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. Involved in the induction of T helper 17 cells (Th17) differentiation. Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation (By similarity).
Other Names:
MALT1; MLT; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT lymphoma-associated translocation; Paracaspase
Antigen Type: synthetic peptide
Antigen Type: MALT1 {ECO:0000303|PubMed:10523859, ECO:0000312|HGNC:HGNC:6819}
Gene ID: 10892
Primary Accession: Q9UDY8
| Is Featured? | No |
|---|
Write Your Own Review