Thyroglobulin (clone PT0653) mouse monoclonal, anti-human

Backgroud: disease:Defects in TG are a cause of some forms of goiter [MIM:188450]. Goiter is an enlargement of the thyroid gland. This is sometimes linked to hypothyroidism.,disease:Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3 (AITD3) [MIM:608175]. AITDs including Graves disease (GD) and Hashimoto thyroiditis (HT), are among the most common human autoimmune diseases. They are complex diseases, which are caused by an interaction between susceptibility genes and nongenetic factors, such as infection.,function:Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3).,online information:Thyroglobulin entry,PTM:Sulfated.,similarity:Belongs to the type-B carboxylesterase/lipase family.,similarity:Contains 11 thyroglobulin type-1 domains.,subunit:Homodimer.,tissue specificity:Thyroid gland specific.,

Synonyms: Thyroglobulin (Tg)

Gene Name: TG

Gene ID: 7038

SwissProt ID: P01266

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.