TIAM (clone F5S F6.2), anti-human
€564.00
In stock
SKU
ARP-21-5257
Catalog Number: 21-5257
Size: 100 µg
Isotype: Mouse IgG2b
Size: 100 µg
Isotype: Mouse IgG2b
Background:
Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in Humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
Clone: F5S F6.2
Isotype: Mouse IgG2b
Source: F5S F6.2 is a Mouse monoclonal IgG2b antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1).
Reactivity: human
Specificity: F5S F6.2 is a Mouse monoclonal directed anti the N-terminal region of Tiam1.
Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applications: Immunohistochemistry (frozen), Western blotting
Storage: Store at 4C, or in small aliquots at -20C.
Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in Humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
Clone: F5S F6.2
Isotype: Mouse IgG2b
Source: F5S F6.2 is a Mouse monoclonal IgG2b antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1).
Reactivity: human
Specificity: F5S F6.2 is a Mouse monoclonal directed anti the N-terminal region of Tiam1.
Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applications: Immunohistochemistry (frozen), Western blotting
Storage: Store at 4C, or in small aliquots at -20C.
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