TIMM8A antibody (clone 2F11), anti-human
€435.00
In stock
SKU
AC-AT4239a
Catalog Number: AC-AT4239a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT4239a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT4239a">Request Information
Background:
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Other Names:
Mitochondrial import inner membrane translocase subunit Tim8 A, Deafness dystonia protein 1, X-linked deafness dystonia protein, TIMM8A, DDP, DDP1, TIM8A
Antigen Type:
Recombinant Protein
Gene Name: TIMM8A
Gene ID: 1678
NCBI Accession: NP_004076.1
Primary Accession: O60220
Other Accession: NM_004085
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Other Names:
Mitochondrial import inner membrane translocase subunit Tim8 A, Deafness dystonia protein 1, X-linked deafness dystonia protein, TIMM8A, DDP, DDP1, TIM8A
Antigen Type:
Recombinant Protein
Gene Name: TIMM8A
Gene ID: 1678
NCBI Accession: NP_004076.1
Primary Accession: O60220
Other Accession: NM_004085
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review