TIMP1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP11199b
Background:
This gene belongs to the TIMP gene family. The proteinsencoded by this gene family are natural inhibitors of the matrixmetalloproteinases (MMPs), a group of peptidases involved indegradation of the extracellular matrix. In addition to itsinhibitory role against most of the known MMPs, the encoded proteinis able to promote cell proliferation in a wide range of celltypes, and may also have an anti-apoptotic function. Transcriptionof this gene is highly inducible in response to many cytokines andhormones. In addition, the expression from some but not allinactive X chromosomes suggests that this gene inactivation ispolymorphic in human females. This gene is located within intron 6of the synapsin I gene and is transcribed in the oppositedirection.
Other Names:
Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP
Gene Name: TIMP1
Gene ID: 7076
Primary Accession: P01033
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene belongs to the TIMP gene family. The proteinsencoded by this gene family are natural inhibitors of the matrixmetalloproteinases (MMPs), a group of peptidases involved indegradation of the extracellular matrix. In addition to itsinhibitory role against most of the known MMPs, the encoded proteinis able to promote cell proliferation in a wide range of celltypes, and may also have an anti-apoptotic function. Transcriptionof this gene is highly inducible in response to many cytokines andhormones. In addition, the expression from some but not allinactive X chromosomes suggests that this gene inactivation ispolymorphic in human females. This gene is located within intron 6of the synapsin I gene and is transcribed in the oppositedirection.
Other Names:
Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP
Gene Name: TIMP1
Gene ID: 7076
Primary Accession: P01033
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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