TIMP1 antibody (clone 4D12), anti-human
€435.00
In stock
SKU
AC-AT4241a
Catalog Number: AC-AT4241a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IP, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IP, E
Request Information AC-AT4241a">Request Information
Background:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq]
Other Names:
Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP
Antigen Type:
Recombinant Protein
Gene Name: TIMP1
Gene ID: 7076
NCBI Accession: NP_003245.1
Primary Accession: P01033
Other Accession: BC007097
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq]
Other Names:
Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP
Antigen Type:
Recombinant Protein
Gene Name: TIMP1
Gene ID: 7076
NCBI Accession: NP_003245.1
Primary Accession: P01033
Other Accession: BC007097
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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