TIMP2 antibody (clone 1C3), anti-human
€435.00
In stock
SKU
AC-AT4245a
Catalog Number: AC-AT4245a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF
Request Information AC-AT4245a">Request Information
Background:
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Other Names:
Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2
Antigen Type:
Recombinant Protein
Gene Name: TIMP2
Gene ID: 7077
NCBI Accession: NP_003246.1
Primary Accession: P16035
Other Accession: BC052605
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Other Names:
Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2
Antigen Type:
Recombinant Protein
Gene Name: TIMP2
Gene ID: 7077
NCBI Accession: NP_003246.1
Primary Accession: P16035
Other Accession: BC052605
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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