TIRAP Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8759b
Background:
Adapter involved in the TLR4 signaling pathway in the innate immune response. TIRAP acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, resulting in cytokine secretion and the inflammatory response.
Other Names:
Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2, TIRAP, MAL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8759b was selected from the C-term region of human TIRAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TIRAP
Gene ID: 114609
Primary Accession: P58753
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Adapter involved in the TLR4 signaling pathway in the innate immune response. TIRAP acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, resulting in cytokine secretion and the inflammatory response.
Other Names:
Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2, TIRAP, MAL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8759b was selected from the C-term region of human TIRAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TIRAP
Gene ID: 114609
Primary Accession: P58753
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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