TKT polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8124
Background:
Transketolase (TK or TKT), a member of the Transketolase family, is a multifunctional protein that plays a role in diabetes, cancer, Alzheimer’s disease and Wernicke-Korsakoff’s syndrome, a latent genetic neurological disorder. Transketolase is also important for the prevention of hyperglycemia-induced vascular damage. Transketolase is a crucial protein in the pentose phosphate pathway (PPP), where it catalyzes several reactions. In combination with Transaldolase, Transketolase functions as a link between glycolysis and the non-oxidative part of the PPP, allowing the cell to adapt to varying metabolic conditions in response to environmental changes. Transketolase activity is detected in small intestine epithelia, liver parenchyma, tongue, cornea and trachea. It is also expressed in the proximal tubules of kidney and in ganglion cells in medulla of the adrenal gland.
Alternative Name:
Transketolase, TX, TKT
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: TKT polyclonal antibody detects endogenous levels of TKT protein.
Immunogen:
Recombinant full length Human TKT.
MW: ~ 68 kDa
Swis Prot.: P29401
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Transketolase (TK or TKT), a member of the Transketolase family, is a multifunctional protein that plays a role in diabetes, cancer, Alzheimer’s disease and Wernicke-Korsakoff’s syndrome, a latent genetic neurological disorder. Transketolase is also important for the prevention of hyperglycemia-induced vascular damage. Transketolase is a crucial protein in the pentose phosphate pathway (PPP), where it catalyzes several reactions. In combination with Transaldolase, Transketolase functions as a link between glycolysis and the non-oxidative part of the PPP, allowing the cell to adapt to varying metabolic conditions in response to environmental changes. Transketolase activity is detected in small intestine epithelia, liver parenchyma, tongue, cornea and trachea. It is also expressed in the proximal tubules of kidney and in ganglion cells in medulla of the adrenal gland.
Alternative Name:
Transketolase, TX, TKT
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: TKT polyclonal antibody detects endogenous levels of TKT protein.
Immunogen:
Recombinant full length Human TKT.
MW: ~ 68 kDa
Swis Prot.: P29401
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review