TLE1 monoclonal (Center), anti-human

TLE1 monoclonal (Center), anti-human

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In stock
SKU
AC-AM1982b
Catalog Number: AC-AM1982b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 381CT18.5.1
Applications: WB
Datasheet

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Background:
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Other Names:
Transducin-like enhancer protein 1, E(Sp1) homolog, Enhancer of split groucho-like protein 1, ESG1, TLE1

Target/Specificity:
This TLE1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1.

Antigen Region:
199-228

Antigen Type: Synthetic Peptide

Gene Name: TLE1
Gene ID: 7088
Primary Accession: Q04724
NCBI Accession: NP_005068.2
Other Accession: NP_005068.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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