TLR2 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13694c
Background:
The protein encoded by this gene is a member of theToll-like receptor (TLR) family which plays a fundamental role inpathogen recognition and activation of innate immunity. TLRs arehighly conserved from Drosophila to humans and share structural andfunctional similarities. They recognize pathogen-associatedmolecular patterns (PAMPs) that are expressed on infectious agents,and mediate the production of cytokines necessary for thedevelopment of effective immunity. The various TLRs exhibitdifferent patterns of expression. This gene is expressed mostabundantly in peripheral blood leukocytes, and mediates hostresponse to Gram-positive bacteria and yeast via stimulation ofNF-kappaB.
Other Names:
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13694c was selected from the Center region of TLR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TLR2 (HGNC:11848)
Gene ID: 7097
Primary Accession: O60603
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of theToll-like receptor (TLR) family which plays a fundamental role inpathogen recognition and activation of innate immunity. TLRs arehighly conserved from Drosophila to humans and share structural andfunctional similarities. They recognize pathogen-associatedmolecular patterns (PAMPs) that are expressed on infectious agents,and mediate the production of cytokines necessary for thedevelopment of effective immunity. The various TLRs exhibitdifferent patterns of expression. This gene is expressed mostabundantly in peripheral blood leukocytes, and mediates hostresponse to Gram-positive bacteria and yeast via stimulation ofNF-kappaB.
Other Names:
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13694c was selected from the Center region of TLR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TLR2 (HGNC:11848)
Gene ID: 7097
Primary Accession: O60603
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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