TLR2 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM8641b
Catalog Number: AC-AM8641b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,κ
Clone Name: 1070CT4.2.3.2
Applications: WB
Datasheet
Request Information
Size: 50 µl, 200 µl
Isotype: mouse IgG1,κ
Clone Name: 1070CT4.2.3.2
Applications: WB
Datasheet
Request Information
Background:
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
Other Names:
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4
Target/Specificity:
This TLR2 Antibody is generated from a mouse immunized with a recombinant protein .
Antigen Type: Recombinant Protein
Gene Name: TLR2 (HGNC:11848)
Gene ID: 7097
Primary Accession: O60603
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
Other Names:
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4
Target/Specificity:
This TLR2 Antibody is generated from a mouse immunized with a recombinant protein .
Antigen Type: Recombinant Protein
Gene Name: TLR2 (HGNC:11848)
Gene ID: 7097
Primary Accession: O60603
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review