TLR5 antibody (clone 4B2), anti-human
€435.00
In stock
SKU
AC-AT4257a
Catalog Number: AC-AT4257a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: E
Request Information AC-AT4257a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: E
Request Information AC-AT4257a">Request Information
Background:
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
Other Names:
Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, TLR5, TIL3
Antigen Type:
Recombinant Protein
Gene Name: TLR5
Gene ID: 7100
NCBI Accession: NP_003259.2
Primary Accession: O60602
Other Accession: NM_003268
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
Other Names:
Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, TLR5, TIL3
Antigen Type:
Recombinant Protein
Gene Name: TLR5
Gene ID: 7100
NCBI Accession: NP_003259.2
Primary Accession: O60602
Other Accession: NM_003268
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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