TLR8 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1508a
Background:
TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Other Names:
Toll-like receptor 8, CD288, TLR8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1508a was selected from the N-term region of human Human TLR8 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TLR8 (HGNC:15632)
Gene ID: 51311
Primary Accession: Q9NR97
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Other Names:
Toll-like receptor 8, CD288, TLR8
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1508a was selected from the N-term region of human Human TLR8 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TLR8 (HGNC:15632)
Gene ID: 51311
Primary Accession: Q9NR97
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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