TLR8 (clone 44B05 ), anti-human antibody
€375.00
In stock
SKU
AC-ABV10409-100
Catalog Number: AC-ABV10409-100
Size: 100 µl
Host: Mouse IgG
Applications: WB, FC
Datasheet
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Size: 100 µl
Host: Mouse IgG
Applications: WB, FC
Datasheet
Request Information
Background:
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and s µggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. TLR8 gene contains three exons, two of which have coding function. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
Other Names:
LR8 , Anti-TLR8 , CD288 , CD 288 , MGC119599 , # MGC119600
Primary Accession: Q9NR97
Other Accession: NP_619542
Gene Name: TLR8
Gene ID: 51311
Concentration (mg/ml): 1.0 mg/ml
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and s µggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. TLR8 gene contains three exons, two of which have coding function. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
Other Names:
LR8 , Anti-TLR8 , CD288 , CD 288 , MGC119599 , # MGC119600
Primary Accession: Q9NR97
Other Accession: NP_619542
Gene Name: TLR8
Gene ID: 51311
Concentration (mg/ml): 1.0 mg/ml
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