TLR9 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13721b
Background:
The protein encoded by this gene is a member of theToll-like receptor (TLR) family which plays a fundamental role inpathogen recognition and activation of innate immunity. TLRs arehighly conserved from Drosophila to humans and share structural andfunctional similarities. They recognize pathogen-associatedmolecular patterns (PAMPs) that are expressed on infectious agents,and mediate the production of cytokines necessary for thedevelopment of effective immunity. The various TLRs exhibitdifferent patterns of expression. This gene is preferentiallyexpressed in immune cell rich tissues, such as spleen, lymph node,bone marrow and peripheral blood leukocytes. Studies in mice andhuman indicate that this receptor mediates cellular response tounmethylated CpG dinucleotides in bacterial DNA to mount an innateimmune response.
Other Names:
Toll-like receptor 9, CD289, TLR9
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13721b was selected from the C-term region of TLR9. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TLR9
Gene ID: 54106
Primary Accession: Q9NR96
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of theToll-like receptor (TLR) family which plays a fundamental role inpathogen recognition and activation of innate immunity. TLRs arehighly conserved from Drosophila to humans and share structural andfunctional similarities. They recognize pathogen-associatedmolecular patterns (PAMPs) that are expressed on infectious agents,and mediate the production of cytokines necessary for thedevelopment of effective immunity. The various TLRs exhibitdifferent patterns of expression. This gene is preferentiallyexpressed in immune cell rich tissues, such as spleen, lymph node,bone marrow and peripheral blood leukocytes. Studies in mice andhuman indicate that this receptor mediates cellular response tounmethylated CpG dinucleotides in bacterial DNA to mount an innateimmune response.
Other Names:
Toll-like receptor 9, CD289, TLR9
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13721b was selected from the C-term region of TLR9. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TLR9
Gene ID: 54106
Primary Accession: Q9NR96
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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