TLR9 antibody (clone 100000000), anti-human
€435.00
In stock
SKU
AC-AT4259a
Catalog Number: AC-AT4259a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT4259a">Request Information
Background:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Other Names:
Toll-like receptor 9, CD289, TLR9
Antigen Type:
Recombinant Protein
Gene Name: TLR9
Gene ID: 54106
NCBI Accession: NP_059138.1
Primary Accession: Q9NR96
Other Accession: BC032713
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Other Names:
Toll-like receptor 9, CD289, TLR9
Antigen Type:
Recombinant Protein
Gene Name: TLR9
Gene ID: 54106
NCBI Accession: NP_059138.1
Primary Accession: Q9NR96
Other Accession: BC032713
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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