TM2D1 Blocking Peptide (N-term)

Background:
The protein encoded by this gene is a beta-amyloidpeptide-binding protein. It contains a structural module related tothat of the seven transmembrane domain G protein-coupled receptorsuperfamily and known to be important in heterotrimeric G proteinactivation. Beta-amyloid peptide has been established to be acausative factor in neuron death and the consequent diminution ofcognitive abilities observed in Alzheimer's disease. This proteinmay be a target of neurotoxic beta-amyloid peptide, and may mediatecellular vulnerability to beta-amyloid peptide toxicity through a Gprotein-regulated program of cell death.

Other Names:
TM2 domain-containing protein 1, Beta-amyloid-binding protein, hBBP, TM2D1, BBP

Target/Specificity:
The synthetic peptide sequence is selected from aa 59-72 of HUMAN TM2D1

Gene Name: TM2D1

Gene ID: 83941
Primary Accession: Q9BX74
Other Accession: NP_114416.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.