TNF α Mouse mAb

Background:
TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions..

Cellular localization: Secreted,Cell membrane

Specificity: Human

Alternative Names:
APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody

Immunogen: Synthetic Peptide

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: WB 1:1,000-2,000, IHC 1:50

Observed band: 17,25kDa

GeneID: 7124

Swiss-Prot No.: P01375

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only