TNF-alpha (clone 1F6), anti-human, mouse, rat
€422.00
In stock
SKU
251690
Catalog Nr.: 251690
Size: 0.1 mg
Isotype: Mouse IgG
Applications: E, WB, IHC, IP
Datasheet
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Size: 0.1 mg
Isotype: Mouse IgG
Applications: E, WB, IHC, IP
Datasheet
Request Information
Protein Family: Cytokines
Pathway and Disease: Signal Transduction, Signaling Molecules and Interaction, Cell Growth and Death, Endocrine System, Immune System, Metabolic Disorders
Description:
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.
Alternate Names: Tumor necrosis factor, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, TNF, TNFA, TNFSF2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500
Accession No.: P01375; NP_000585
Antigen: Recombinant human TNF-alpha protein.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Ock S. et al. 2015. Division of Endocrinology and Metabolism, Seoul. Jan
157(1):336-45. PMID: 26469138.
[2] Moore S et al. 2012. Elsevier. Veterinary Immunology and Immunopathology. 148(3-4):348-352. PMID# 22840733.
[3] Tong H et al. 2011. Endocrine Biology. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 294(3):445-452. PMID# 21308995.
Pathway and Disease: Signal Transduction, Signaling Molecules and Interaction, Cell Growth and Death, Endocrine System, Immune System, Metabolic Disorders
Description:
Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.
Alternate Names: Tumor necrosis factor, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, TNF, TNFA, TNFSF2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500
Accession No.: P01375; NP_000585
Antigen: Recombinant human TNF-alpha protein.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Ock S. et al. 2015. Division of Endocrinology and Metabolism, Seoul. Jan
157(1):336-45. PMID: 26469138.
[2] Moore S et al. 2012. Elsevier. Veterinary Immunology and Immunopathology. 148(3-4):348-352. PMID# 22840733.
[3] Tong H et al. 2011. Endocrine Biology. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 294(3):445-452. PMID# 21308995.
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