TNF-alpha (clone 2A9B9), anti-human
€478.00
In stock
SKU
252734
Protein Family: Cytokines
Pathway and Disease: Signal Transduction, Signaling Molecules and Interaction, Cell Growth and Death, Endocrine System, Immune System, Metabolic Disorders
Description:
TNF-alpha (Tumor necrosis factor alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.
Alternate Names: Tumor necrosis factor, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, TNF, TNFA, TNFSF2
Application Notes: E: 1:10000; WB: 1:500-1:2000
Accession No.: P01375
Antigen: Recombinant Human TNF-alpha
Format: Each vial contains 0.1 mg IgG (1 mg/ml) in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signal Transduction, Signaling Molecules and Interaction, Cell Growth and Death, Endocrine System, Immune System, Metabolic Disorders
Description:
TNF-alpha (Tumor necrosis factor alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.
Alternate Names: Tumor necrosis factor, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, TNF, TNFA, TNFSF2
Application Notes: E: 1:10000; WB: 1:500-1:2000
Accession No.: P01375
Antigen: Recombinant Human TNF-alpha
Format: Each vial contains 0.1 mg IgG (1 mg/ml) in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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