TNF alpha (Humicade) (clone ), anti-human antibody
€655.00
In stock
SKU
AC-ABV11787-200
Catalog Number: AC-ABV11787-200
Size: 200 µg
Host: recombinant human IgG4 antibody
Applications: E
Datasheet
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Size: 200 µg
Host: recombinant human IgG4 antibody
Applications: E
Datasheet
Request Information
Background:
The antibody binds specifically to TNF-alpha, a pro-inflammatory cytokine which stimulates release of other cytiokines e.g. IL-1, IL-6 and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB.
Other Names:
Tumor necrosis factor superfamily member 2, TNFSF2, TNFA
Primary Accession: P01375
Gene Name: TNF
Gene ID: 7124
The antibody binds specifically to TNF-alpha, a pro-inflammatory cytokine which stimulates release of other cytiokines e.g. IL-1, IL-6 and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB.
Other Names:
Tumor necrosis factor superfamily member 2, TNFSF2, TNFA
Primary Accession: P01375
Gene Name: TNF
Gene ID: 7124
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