TNF Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13532b
Background:
This gene encodes a multifunctional proinflammatorycytokine that belongs to the tumor necrosis factor (TNF)superfamily. This cytokine is mainly secreted by macrophages. Itcan bind to, and thus functions through its receptorsTNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in theregulation of a wide spectrum of biological processes includingcell proliferation, differentiation, apoptosis, lipid metabolism,and coagulation. This cytokine has been implicated in a variety ofdiseases, including autoimmune diseases, insulin resistance, andcancer. Knockout studies in mice also suggested the neuroprotectivefunction of this cytokine.
Other Names:
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Tumor necrosis factor, membrane form, N-terminal fragment, NTF, Intracellular domain 1, ICD1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor, soluble form, TNF, TNFA, TNFSF2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13532b was selected from the C-term region of TNF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TNF
Gene ID: 7124
Primary Accession: P01375
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a multifunctional proinflammatorycytokine that belongs to the tumor necrosis factor (TNF)superfamily. This cytokine is mainly secreted by macrophages. Itcan bind to, and thus functions through its receptorsTNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in theregulation of a wide spectrum of biological processes includingcell proliferation, differentiation, apoptosis, lipid metabolism,and coagulation. This cytokine has been implicated in a variety ofdiseases, including autoimmune diseases, insulin resistance, andcancer. Knockout studies in mice also suggested the neuroprotectivefunction of this cytokine.
Other Names:
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Tumor necrosis factor, membrane form, N-terminal fragment, NTF, Intracellular domain 1, ICD1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor, soluble form, TNF, TNFA, TNFSF2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13532b was selected from the C-term region of TNF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TNF
Gene ID: 7124
Primary Accession: P01375
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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