TNF Receptor II TNFRSF1B monoclonal, anti-human, mouse, rat

TNF Receptor II TNFRSF1B monoclonal, anti-human, mouse, rat

€455.00
In stock
SKU
AC-ABO14216
Catalog Number: AC-ABO14216
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, IP, FC
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Description: Anti-TNF Receptor II TNFRSF1B Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Protein Function:
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity..

Other Names: Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Etanercept, Tumor necrosis factor receptor superfamily member 1b, membrane form, Tumor necrosis factor-binding protein 2, TBP-2, TBPII, TNFRSF1B, TNFBR, TNFR2

Clone Name(s):
Clone: AAIB-20

Subcellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein.

Gene ID: 7133

Immunogen: A synthesized peptide derived from human TNF Receptor II

Calculated MW: 48291

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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