TNFAIP8L1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60529
Background:
Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Alternative Name:
Tumor necrosis factor alpha-induced protein 8-like protein 1, TNF alpha-induced protein 8-like protein 1, TNFAIP8-like protein 1, TNFAIP8L1
Application Dilution: WB: 1:500~1:1000
Specificity: TNFAIP8L1 polyclonal antibody detects endogenous levels of TNFAIP8L1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TNFAIP8L1
MW: ~ 21 kDa
Swis Prot.: Q8WVP5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Alternative Name:
Tumor necrosis factor alpha-induced protein 8-like protein 1, TNF alpha-induced protein 8-like protein 1, TNFAIP8-like protein 1, TNFAIP8L1
Application Dilution: WB: 1:500~1:1000
Specificity: TNFAIP8L1 polyclonal antibody detects endogenous levels of TNFAIP8L1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TNFAIP8L1
MW: ~ 21 kDa
Swis Prot.: Q8WVP5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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